Featured Publications

  • Dahal L, Ghojoghnejad M, Vancoillie L, Ghosh D, Bhandari Y, Kim D, Ho FC, Tushar FI, Luo S, Lafata KJ, Abadi E, Samei E, Lo JY, Segars WP.
    XCAT 3.0: A comprehensive library of personalized digital twins derived from CT scans.
    Medical Image Analysis. 2025;103:103636. Epub 2025/05/03. [Foundation]
    https://doi.org/10.1016/j.media.2025.103636

  • Samei E.
    The future of in silico trials and digital twins in medicine.
    PNAS Nexus.2025;4(5):pgaf123 Epub 2025/04/18. [Foundation]
    https://doi.org/10.1093/pnasnexus/pgaf123

  • Wang AJ, Tushar FI, Harowicz MR, Tong BC, Lafata KJ, Tailor TD, Lo JY.
    Duke Lung Cancer Screening (DLCS) Dataset: A Reference Dataset of Annotated Low-dose Screening Thoracic CT.
    Radiology Artificial Intelligence.2025;e240248 Epub 2025/04/16. [Foundation]
    https://doi.org/10.1148/ryai.240248

  • Tushar FI, Vancoillie L, McCabe C, Kavuri A, Dahal L, Harrawood B, Fryling M, Zarei M, Sotoudeh-Paima S, et al.
    Virtual lung screening trial (VLST): An in silico study inspired by the national lung screening trial for lung cancer detection.
    Medical Image Analysis.2025;103:103576 Epub 2025/04/05. [Foundation]
    https://doi.org/10.1016/j.media.2025.103576

  • J. R. Rajagopal, F. R. Schwartz, C. McCabe, F. Farhadi, M. Zarei, F. Ria, E. Abadi, P. Segars, J. C. Ramirez-Giraldo, E. C. Jones, T. Henry, D. Marin, and E. Samei
    Technology Characterization Through Diverse Evaluation Methodologies: Application to Thoracic Imaging in Photon-Counting Computed Tomography.
    J Comput Assist Tomogr. 2024;49(1):113-124 Epub 2024/04/15. [Foundation]

  • T. J. Sauer, A. J. Buckler, E. Abadi, M. Daubert, P. S. Douglas, E. Samei, and W. P. Segars
    Development of physiologically-informed computational coronary artery plaques for use in virtual imaging trials.
    Medical Physics. 2024;51(3). Epub 2024/03/21. [Foundation]
    https://doi.org/10.1002/mp.16959

  • S. Sotoudeh-Paima, W. P. Segars, D. Ghosh, S. Luo, E. Samei, and E. Abadi
    A systematic assessment and optimization of photon-counting CT for lung density quantifications.
    Medical Physics. 2024;51(4) Epub 2024/02/18. [Foundation]
    https://doi.org/10.1002/mp.16987

  • T. J. Sauer, C. McCabe, E. Abadi, E. Samei, and W. P. Segars
    Surface-based anthropomorphic bone structures for use in high-resolution simulated medical imaging.
    Phys Med Biol. 2023;69(1). Epub 2023/12/28. [Foundation]
    https://doi.org/10.1088/1361-6560/ad1275

  • M. Zarei, E. Abadi, W. P. Segars, and E. Samei
    Coronary stenosis quantification in cardiac computed tomography angiography: multi-factorial optimization of image quality and radiation dose.
    J Med Imaging (Bellingham). 2023;10(6):063502. Epub 2023/12/27. [Foundation]
    https://doi.org/10.1117/1.JMI.10.6.063502

  • Abadi E, McCabe C, Harrawood B, Sotoudeh-Paima S, Segars W, Samei E.
    Development and clinical applications of a virtual imaging framework for optimizing photon-counting CT.
    SPIE Medical Imaging. 2022;12031.
    https://doi.org/10.1117/12.2612079

  • Alsaihati N, Solomon J, Samei E.
    Development and validation of a generic image-based noise addition software for simulating reduced dose computed tomography images using synthetic projections.
    SPIE Medical Imaging. 2022;12031.
    https://doi.org/10.1117/12.2612666

  • Clark D, Abadi E, Felice N, Segars WP, Samei E, Badea C.
    Cardiac CT reconstruction for vendor-neutral virtual imaging trials.
    SPIE Medical Imaging. 2022;12031.
    https://doi.org/10.1117/12.2612950

  • Dahal L, Tushar FI, Abadi E, Fricks RB, Mazurowski M, Segars WP, Samei E, Lo J.
    Virtual versus reality: external validation of COVID-19 classifiers using XCAT phantoms for chest radiography.
    SPIE Medical Imaging. 2022;12031.

  • McCabe C, Zarei M, Segars WP, Samei E, Abadi E.
    Optimization of imaging parameters of an investigational photon-counting CT prototype for lung lesion radiomics.
    SPIE Medical Imaging. 2022;12033.
    https://doi.org/10.1117/12.2612973

  • Ria F, Jadick G, Abadi E, Solomon J, Samei E.
    Comparing two different noise magnitude estimation methods in CT using virtual imaging trials.
    SPIE Medical Imaging. 2022;12031.
    https://doi.org/10.1117/12.2612219

  • Shaker K, Häggmark I, Nyrén S, Al-Amiry B, Abadi E, Segars W, Samei E, Hertz H.
    Virtual study of phase-contrast thoracic imaging.
    SPIE Medical Imaging. 2022;PC12031.

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