A virtual platform for evaluating medical imaging technologies from design to use

Three images showing anatomy of a phantom, ct scanner, and a heat map of scan
National Institutes of Health (NIH)

CVIT is a National Center for Biomedical Imaging and Bioengineering supported by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) and operated at Duke University.

Phantoms in Space

Two phantoms the Center helped with, Helga and Zohar, are set to launch on NASA’s Artemis I rocket. The phantoms will be taking a trip around the moon to measure radiation exposure as they travel through space. The ultimate goal is to explore the possibility of sending humans to Mars.

A New Methodology

We offer an efficient methodology for evaluating imaging technologies and applications in silico using computational models simulating the patient, the imaging system, and the image reader.

These models comprise our three technology, research, and development (TR&D) endeavors, where we continue to provide realistic computational models of human anatomy (virtual patients), state-of-the-art CT scanners (virtual scanners), and clinically relevant image analysis (virtual readers).

The TR&Ds work synergistically to offer comprehensive resources and essential training to partners through our various collaborative and service projects as well as training and dissemination efforts.

Recently Shared Software

  • CVIT Observer Models

    CVIT Observer Models
    Toolbox for mathematical observer model calculations, designed to produce image quality figures of merit from simulated image data from CVIT.
  • Pysarfe Radiomics Pipeline

    Pysarfe Radiomics Pipeline
    Pipeline includes eleven unsupervised binary segmentation methods and a feature extraction module to calculate various radiomics features for an image and its binary segmentation pair.

Recently Shared Data


CVIT contribution at SPIE Medical Imaging 2022 conference: 18 scientific presentations and one special course.

The Center for Virtual Imaging Trials is presenting 18 scientific studies at SPIE Medical Imaging 2022 conference that will be held in San Diego (California) 20-24 February. The SPIE medical imaging chapter focuses on the latest advances in image processing

Computerized Human Organ Models

A new NIH R01 grant just awarded to Ehsan Abadi

A new NIH R01 grant titled “Accuracy and Precision in CT Quantification of COPD Through Virtual Imaging Trials” was just awarded to Ehsan Abadi, one of the principal investigators of the Center for Virtual Imaging Trials.

Drs. Ehsan Samei and Daniele Marin stand in front of Siemens CT Scanner

Duke Radiology installs one of the first prototype photon-counting CT systems worldwide

Duke Radiology has obtained an innovative new generation of photon-counting computed tomography from Siemens Healthineers, one of the first research prototypes worldwide.

Important Metrics

Simulated CT data for three male anatomies


Rows of phantoms ranging from adults to children


Highly detailed anatomy for the human brain including ~100 structures and vessel


Looking through CT Scanner at Phantom


Rows of phantoms ranging from adults to children


Highly detailed anatomy of a laboratory mouse