Advancing Skeletal Dosimetry Through Detailed Mesh-Based Skeletal Models for Adults & Children

Forum Details

Date: Friday, March 20, 2026

Speakers: Wesley Bolch, PhD from the University of Florida

Skeletal dosimetry is particularly challenging because of the complex microstructure of bone tissues and the need to accurately assess radiation dose to highly radiosensitive regions such as red bone marrow and the endosteum. Although several three-dimensional skeletal models have been developed, existing approaches have been limited by insufficient spatial resolution and a lack of pediatric skeletal models.

In this talk, Dr. Bolch presents the development of a comprehensive library of mesh-based skeletal models for both adults and children derived from micro-CT imaging data. He describes the automated workflow used to generate anatomically realistic skeletal microstructures and discuss their implementation in Monte Carlo radiation transport simulations. Dr. Bolch also presents specific absorbed fraction (SAF) data for alpha particles and electrons and compare the performance of the new mesh-based models with conventional voxel-based approaches. The results demonstrate substantial improvements in skeletal dosimetry accuracy, particularly for pediatric dose assessment and age-dependent internal exposures.